|Name||Phencyclidine Urine Rapid Test (Strip/cassette)|
|Category Name||Drug Tests|
|Test||25 or 50 tests|
The PCP Rapid Test (Urine) is a rapid chromatographic immunoassay for the detection of Phencyclidine in urine at a cut-off concentration of 25 ng/mL.
Materials Provided with PCP drug Rapid Test kit:
1. PCP Test Device
The test contains mouse monoclonal anti-Phencyclidine antibody-coupled particles and Phencyclidine-protein conjugate. A goat antibody is employed in the control line system.
2. Instructions for use
Materials required, not Provided:
1. Urine collection container
2. Timer or clock
PCP Rapid Test kit Background Information
Phencyclidine, also known as PCP, is a hallucinogen that was first marketed as a surgical anesthetic in the 1950’s. It was removed from the market because patients receiving it became delirious and experienced hallucinations.
Phencyclidine is used in powder, capsule, and tablet form. The powder is either snorted or smoked after mixing it with marijuana or vegetable matter. PCP is most commonly administered by inhalation but can be used intravenously, intra-nasally, and orally. After low doses, the user thinks and acts swiftly and experiences mood swings from euphoria to depression. Self-injurious behavior is one of the devastating effects of PCP.
PCP can be found in urine within 4 to 6 hours after use and will remain in urine for 7 to 14 days, depending on factors such as metabolic rate, user’s age, weight, activity, and diet. PCP is excreted in the urine as unchanged drug (4% to 19%) and conjugated metabolites (25% to 30%).
PCP drug Rapid Test Principle
The PCP Rapid Test (Urine) is an immunoassay based on the principle of competitive binding. Drugs that may be present in the urine specimen compete against the drug conjugate for binding sites on the antibody.
During testing, a urine specimen migrates upward by capillary action. Phencyclidine, if present in the urine specimen below 25 ng/mL, will not saturate the binding sites of the antibody in the test. The antibody coated particles will then be captured by immobilized Phencyclidine conjugate and a visible colored line will show up in the test line region. The colored line will not form in the test line region if the Phencyclidine level exceeds 25 ng/mL because it will saturate all the binding sites of anti-Phencyclidine antibodies.
A drug-positive urine specimen will not generate a colored line in the test line region because of drug competition, while a drug-negative urine specimen or a specimen containing a drug concentration less than the cut-off will generate a line in the test line region. To serve as a procedural control, a colored line will always appear at the control line region indicating that proper volume of specimen has been added and membrane wicking has occurred.